"Beautiful anomaly" by Sonja Lehmann

"Beautiful anomaly", submitted by Sonja Lehmann, from the Intitute of Molecular and Cellular Anatomy, in Aachen, Germany, is the second image selected by the Scientific Committee of Targeting Mitochondria 2019 for the 10th anniversary.

4 PC-Keratinocyte MitoTimer SonjaLehmann

Immortalized human keratinocytes derived from patients with the hereditary skin disease Pachyonychia congenita were transfected with MitoTimer. Confocal live-cell imaging revealed the bizarre mitochondrial morphology that rarely occurs in atypical cells.